Understanding hidradenitis suppurativa

Almirall announces a collaboration with the University of Michigan to gain understanding of disease drivers in hidradenitis suppurativa

BARCELONA, Spain, March 15th 2022 – Almirall, S.A. (ALM), a global biopharmaceutical company focused on skin health, today announced a collaboration agreement with the University of Michigan to accelerate the understanding of the factors that trigger hidradenitis suppurativa, a chronic and inflammatory skin condition. Through this partnership, Almirall’s expertise in skin diseases will be combined with the knowledge of the Dermatology Department at the University of Michigan, led by Dr. Johann E. Gudjonsson, to investigate relevant aspects of this disease such as chronic disease dissection and fibrosis.

Hidradenitis suppurativa is caused by occlusion of the hair follicle and it affects broad areas of the body such as the axillae, inguinal, anogenital, gluteal and inframammary area. The dilated hair follicle ruptures, spilling its contents into the dermis and causing an inflammatory response, nodules, abscesses and, in later stages, sinus tract formation and scarring.

Despite substantial advances in the understanding of the disease in recent years, its pathogenesis is not fully understood and it is associated with relevant comorbidities that significantly decrease the quality of life of patients. Moreover, the treatment of hidradenitis suppurativa is challenging and often requires surgery.

This partnership aims for a deeper understanding of hidradenitis suppurativa, a complex disease with large unmet medical needs. An in-depth knowledge of disease drivers will enable novel therapeutic approaches to provide treatment options for patients suffering from this severe condition”, stated Dr. Thomas Huber, Research Director at Almirall.

 “This collaboration will provide resources that we hope will greatly increase our understanding of the critical disease mechanisms that drive the pathogenesis of hidradenitis using state-of-the-art technologies and analytics”, said Johann E. Gudjonsson, M.D., Ph.D., professor of dermatology at University of Michigan Health, Michigan Medicine. “We envision that this will greatly accelerate the path from discovery to novel treatments, which will help us better treat this disease.”

Dr. Johan Gudjonsson has been a paid consultant for Almirall since 2019.

For more information, please visit almirall.com


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